Canine Atopic Dermatitis (CAD) di Rumah Sakit Hewan Pendidikan IPB University
Keywords:
canine atopic dermatitis, terapi, kulit, penyakit, anjing
Abstract
Canine Atopic Dermatitis (CAD) adalah penyakit kulit kronis yang dipengaruhi oleh faktor genetik dan lingkungan. Studi kasus ini membahas penanganan seekor anjing Siberian Husky berusia 7 tahun yang didiagnosis dengan CAD di Rumah Sakit Hewan Pendidikan IPB University. Gejala utama yang dialami meliputi pruritus, eritema, dan lesi kulit yang disebabkan oleh infeksi sekunder. Terapi yang diberikan termasuk penggunaan prednisolon sebagai antiinflamasi, Transfer Factor untuk mendukung sistem imun, dan produk topikal seperti Allerdone untuk mengatasi gatal. Selain itu, sampo antibakteri dan antijamur, serta suplemen kulit Coatex, diberikan untuk mengelola kondisi kulit. Edukasi terhadap pemilik mengenai pengelolaan jangka panjang sangat penting untuk menjaga kualitas hidup anjing dan mengurangi beban psikologis serta finansial pemilik. Studi ini menekankan pentingnya pendekatan terapi multimodal dalam menangani CAD.
References
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[21] Scott DW, Miller WH, Griffin CE. 2001. Muller dan Kirk's Small Animal Dermatology, edisi ke-6. Philadelphia: WB Saunders Company.
[22] Carlotti D. 2004. Shampoo Therapy In Veterinary Dermatology. 29th World Congress of the World Small Animal Veterinary Association; 2004 Oct 6-9; Rhodes, Greece.
[23] Plumb DC. 2008. Plumb’s Veterinary Drug Handbook. 6th ed. Stockholm, Wis. : Ames, Iowa: PharmaVet ; Distributed by Blackwell Pub.
[24] Pushp MK, Soni Y, Meen MK, Tiwari RK. 2022. Therapeutic management of canine atopic dermatitis in a German shepherd dog: a case report. The Pharma Innovation. 11(7): 3382-3384.
[25] Ferreira TC, de Carvalho VM, da Cunha MGMCM, Pinheiro DCS. 2022. Canine atopic dermatitis: report of ten cases. Research, Society and Development. 11(4): 1-10.
[26] Olivry T, Banovic F. 2019. Treatment of canine atopic dermatitis: time to revise our strategy?. Veterinary Dermatology. 30: 87-90.
[27] Olivry T, Deboer D, Favrot C, Jackson HA, Mueller RS, Nutall T, Prélaud P. 2015. International Committee on Allergic Diseases of Animals. (2015). Treatment of canine atopic dermatitis: 2015 updated guidelines from the
International Committee on Allergic Diseases of Animals (ICADA). BMC Veterinary Research. 11: 210.
[28] Pareek A, Kumari L, Pareek A, Chaudhary S, Ratan Y, Janmeda P, Chuturgoon S, Chuturgoon A. 2024. Unraveling Atopic Dermatitis: Insights into Pathophysiology, Therapeutic Advances, and Future Perspectives. Cells. 13(5):425.doi:10.3390/cells13050425.
[29] Hashimoto T, Yokozeki H, Karasuyama H, Satoh T. 2023. IL-31–generating network in atopic dermatitis comprising macrophages, basophils, thymic stromal lymphopoietin, and periostin. J. Allergy Clin. Immunol. 151: 737–746.
[30] Celebi SZ, Ozdel OB, Cerci P, Turk, M, Gorgulu AB, Akdis M, Altiner S, Ozbey U, Ogulur I, Mitamura Y, et al. 2022. Epithelial barrier hypothesis: Effect of the external exposome on the microbiome and epithelial barriers in allergic disease. Allergy. 77: 1418–1449.
[31] Puckett Y, Gabbar A, Bokhari AA. 2024. Prednisone. Di dalam: StatPearls. [internet] Treasure Island (FL). Treasure Island (FL): StatPearls Publishing. [diunduh 2024 Sep 25]. Tersedia pada:
http://www.ncbi.nlm.nih.gov/books/NBK534809/
[32] Gadeyne C, Little P, King VL, Edwards N, Davis K, Stegemann MR. 2014. Efficacy of oclacitinib (Apoquel®) compared with prednisolone for the control of pruritus and clinical signs associated with allergic dermatitis in client-owned dogs in Australia. Vet Dermatol. 25(6):512-e86.doi:10.1111/vde.12166.
[33] Olivry T, Lokianskiene V, Blanco A, Mestre PD, Bergvall K, Beco L. 2023. A randomised controlled trial testing the rebound‐preventing benefit of four days of prednisolone during the induction of oclacitinib therapy in dogs with atopic dermatitis. Veterinary Dermatology. 34(2):99–106.doi:10.1111/vde.13134.
[34] Bloom P. 2014. Canine superficial bacterial folliculitis: Current understanding of its etiology, diagnosis and treatment. The Veterinary Journal. 199: 217-222.
[35] Ferreira TC, Guedes RFM, Bezerra BMO, Nunes-Pinheiro DCS. 2019. Mupirocin pemphigus-like drug reaction in a dog. Acta Scientiae Veterinariae. 47: 1-6.
[36] Larsson CE, Lucas R. 2020. Tratado de medicina externa: dermatologia veterinária. (2a ed.). Interbook.
[37] Abba C, Mussa PP, Vercelli A, Raviri G. 2005. Essential fatty acids supplementation in different-stage atopic dogs fed on a controlled diet. J. Anim. Physiol. Anim. Nutr. 89: 203–207. DOI: 10.1111/j.1439-0396.2005.00541.x.
[38] Marsella R, Nicklin C, Lopez J. 2006. Studies on the role of routes of allergen exposure in high IgE-producing beagle dogs sensitized to house dust mites. Vet Dermatol. 17(5): 306–312.
[39] Olivry T, DeBoer DJ, Favrot C, Jackson HA, Mueller RS, Nuttall T, Prélaud P. 2010. International Task Force on Canine Atopic Dermatitis. Treatment of canine atopic dermatitis: 2010 clinical practice guidelines from the International Task Force on Canine Atopic Dermatitis. Vet Dermatol. 21(3): 233-48. DOI: 10.1111/j.1365-3164.2010.00889.x.
[40] Anturaniemi J, Zaldívar-López S, Savelkoul FJH, Elo K, Hielm-Björkman A. 2020. The effect of atopic dermatitis and diet on the skin transcriptome in staffordshire bull terriers. Frontiers in Veterinary Science. DOI: 10.3389/fvets.2020.552251.
[41] Masuda K, Sato A, Tanaka A, Kumagai A. 2020. Hydrolyzed diets may stimulate food-reactive lymphocytes in dogs. J Vet Med Sci. 82(2): 177-183. DOI: 10.1292/jvms.19-0222.
[2] Noli C, Colombo S, Cornegliani L, Ghibaudo G, Persico P, Vercelli A, Galzerano M. 2011. Quality of life of dogs with skin disease and of their owners. Part 2: administration of a questionnaire in various skin diseases and correlation to efficacy of therapy. Vet Dermatol. 22(4): 344-51. DOI: 10.1111/j.1365-3164.2011.00956.x.
[3] Linek M, Favrot C. 2010. Impact of canine atopic dermatitis on the health-related quality of life of affected dogs and quality of life of their owners. Vet. Dermatol. 21: 456–462. DOI: 10.1111/j.1365-3164.2010.00899.x.
[4] Bizikova P, Santoro D, Marsella R, Nuttall T, Eisenschenk MN, Pucheu-Haston CM. 2015. Review: Clinical and histological manifestations of canine atopic dermatitis. Vet Dermatol. 26(2): 79-e24. DOI: 10.1111/vde.12196.
[5] Hensel P, Santoro D, Favrot C, Hill P, Griffin C. 2015. Canine atopic dermatitis: detailed guidelines for diagnosis and allergen identification. BMC Vet Res. 11: 196. DOI: 10.1186/s12917-015-0515-5.
[6] Outerbridge CA, Jordan TJ. 2021. Current knowledge on canine atopic dermatitis: pathogenesis and treatment. Adv Small Anim. 2: 101–115. DOI: 10.1016/j.yasa.2021.07.004.
[7] Couceiro GA, Ribeiro SMM, Monteiro MM, Meneses AMC, Sousa SKS, Coutinho LN. 2021. Prevalence of canine atopic dermatitis at the veterinary hospital of the “universidade federal rural da Amazônia” in Belém/Pará, Brazil. Pesquisa Veterinária Brasileira. 41. DOI: 10.1590/1678-5150-pvb-6778.
[8] Bizikova P, Pucheu‐Haston CM, Eisenschenk MN, Marsella R, Nuttall T, Santoro D. 2015. Role of genetics and the environment in the pathogenesis of canine atopic dermatitis. Vet Dermatol. 26(2): 95–e26. DOI: 10.1111/vde.12198.
[9] Drechsler Y, Dong C, Clark DE, Kaur G. 2024. Canine atopic dermatitis: Prevalence, impact, and management strategies. Veterinary Medicine: Research and Reports. 15: 15–29.
[10] Marks SL. 2022. Anemia in Dogs. MSD Veterinary Manual. Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University.
[11] Widyanti AI, Suartha IN, Erawan IGMK, Anggreni LD, Sudimartini LM. 2018. Hemogram Anjing Penderita Dermatitis Kompleks. Indonesia Medicus Veterinus. 7(5): 576-587.
[12] Guyton AC. 1991. Fisiologi Kedokteran, Edisi ke-3. Jakarta (ID): EGC.
[13] Evans LK, Knowles TG, Werrett G, Holt PE. 2009. The efficacy of chlorhexidine gluconate in canine skin preparation
- practice survey and clinical trials. J Small Anim Pract. 50(9): 458-65. DOI: 10.1111/j.1748-5827.2009.00773.x.
[14] Zhao Y. Brown MB, Jones MA. 2010. The topical delivery of benzoyl peroxide using elegant dynamic hydrofluoroalkane foams. Journal of Pharmaceutical Sciences. 99(3): 1384-98.DOI: https://doi.org/10.1002/jps.21933.
[15] Gedük AS, Atsız S. 2022. LC-MS/MS phenolic composition of peach (Prunus persica (L.) Batsch) extracts and an evaluation of their antidiabetic, antioxidant, and antibacterial activities. South African Journal of Botany. 147: 636-645. DOI: https://doi.org/10.1016/j.sajb.2022.02.026.
[16] Kotha P, Badri KR, Nagalapuram R, Allagadda R, Chippada AR. 2017. Anti-Diabetic potential of the leaves of Anisomeles malabarica in streptozotocin induced diabetic rats. Cellular Physiology and Biochemistry. 43 (4): 1689–1702. DOI: https://doi.org/10.1159/000484030.
[17] Lisonbee D, Hennen WJ, Daugherty FJ. 2005. Compositions including different types of Transfer factor, methods for making the compositions, and methods of treatment using the compositions. USPTO Patent Applications.
[18] Abdillah MR, Lamid M, Budi DS. 2022. Pengaruh pemberian formula Transfer Factor terhadap peningkatan limfosit dan Survival Rate ikan mas koi (Cyprinus carpio) yang terinfeksi Aeromonas hydrophila. Journal of Basic Medical Veterinary. 11(1): 31-36.
[19] Marsh KA, Ruedisueli FL, Coe SL, Watson TGD. 2000. Effects of zinc and linoleic acid supplementation on the skin and coat quality of dogs receiving a complete and balanced diet. Veterinary Dermatology. 11(4):277-284. DOI: 10.1046/j.1365-3164.2000.00202.x
[20] Marchegiani A, Fruganti A, Spaterna A, Vedove ED, Cachetti B, Massimini M, Pierro FD, Gavazza A, Cerquetella M. 2020. Impact of nutritional supplementation on canine dermatological disorders. Vet Sci. 7(2): 38. DOI: 10.3390/vetsci7020038.
[21] Scott DW, Miller WH, Griffin CE. 2001. Muller dan Kirk's Small Animal Dermatology, edisi ke-6. Philadelphia: WB Saunders Company.
[22] Carlotti D. 2004. Shampoo Therapy In Veterinary Dermatology. 29th World Congress of the World Small Animal Veterinary Association; 2004 Oct 6-9; Rhodes, Greece.
[23] Plumb DC. 2008. Plumb’s Veterinary Drug Handbook. 6th ed. Stockholm, Wis. : Ames, Iowa: PharmaVet ; Distributed by Blackwell Pub.
[24] Pushp MK, Soni Y, Meen MK, Tiwari RK. 2022. Therapeutic management of canine atopic dermatitis in a German shepherd dog: a case report. The Pharma Innovation. 11(7): 3382-3384.
[25] Ferreira TC, de Carvalho VM, da Cunha MGMCM, Pinheiro DCS. 2022. Canine atopic dermatitis: report of ten cases. Research, Society and Development. 11(4): 1-10.
[26] Olivry T, Banovic F. 2019. Treatment of canine atopic dermatitis: time to revise our strategy?. Veterinary Dermatology. 30: 87-90.
[27] Olivry T, Deboer D, Favrot C, Jackson HA, Mueller RS, Nutall T, Prélaud P. 2015. International Committee on Allergic Diseases of Animals. (2015). Treatment of canine atopic dermatitis: 2015 updated guidelines from the
International Committee on Allergic Diseases of Animals (ICADA). BMC Veterinary Research. 11: 210.
[28] Pareek A, Kumari L, Pareek A, Chaudhary S, Ratan Y, Janmeda P, Chuturgoon S, Chuturgoon A. 2024. Unraveling Atopic Dermatitis: Insights into Pathophysiology, Therapeutic Advances, and Future Perspectives. Cells. 13(5):425.doi:10.3390/cells13050425.
[29] Hashimoto T, Yokozeki H, Karasuyama H, Satoh T. 2023. IL-31–generating network in atopic dermatitis comprising macrophages, basophils, thymic stromal lymphopoietin, and periostin. J. Allergy Clin. Immunol. 151: 737–746.
[30] Celebi SZ, Ozdel OB, Cerci P, Turk, M, Gorgulu AB, Akdis M, Altiner S, Ozbey U, Ogulur I, Mitamura Y, et al. 2022. Epithelial barrier hypothesis: Effect of the external exposome on the microbiome and epithelial barriers in allergic disease. Allergy. 77: 1418–1449.
[31] Puckett Y, Gabbar A, Bokhari AA. 2024. Prednisone. Di dalam: StatPearls. [internet] Treasure Island (FL). Treasure Island (FL): StatPearls Publishing. [diunduh 2024 Sep 25]. Tersedia pada:
http://www.ncbi.nlm.nih.gov/books/NBK534809/
[32] Gadeyne C, Little P, King VL, Edwards N, Davis K, Stegemann MR. 2014. Efficacy of oclacitinib (Apoquel®) compared with prednisolone for the control of pruritus and clinical signs associated with allergic dermatitis in client-owned dogs in Australia. Vet Dermatol. 25(6):512-e86.doi:10.1111/vde.12166.
[33] Olivry T, Lokianskiene V, Blanco A, Mestre PD, Bergvall K, Beco L. 2023. A randomised controlled trial testing the rebound‐preventing benefit of four days of prednisolone during the induction of oclacitinib therapy in dogs with atopic dermatitis. Veterinary Dermatology. 34(2):99–106.doi:10.1111/vde.13134.
[34] Bloom P. 2014. Canine superficial bacterial folliculitis: Current understanding of its etiology, diagnosis and treatment. The Veterinary Journal. 199: 217-222.
[35] Ferreira TC, Guedes RFM, Bezerra BMO, Nunes-Pinheiro DCS. 2019. Mupirocin pemphigus-like drug reaction in a dog. Acta Scientiae Veterinariae. 47: 1-6.
[36] Larsson CE, Lucas R. 2020. Tratado de medicina externa: dermatologia veterinária. (2a ed.). Interbook.
[37] Abba C, Mussa PP, Vercelli A, Raviri G. 2005. Essential fatty acids supplementation in different-stage atopic dogs fed on a controlled diet. J. Anim. Physiol. Anim. Nutr. 89: 203–207. DOI: 10.1111/j.1439-0396.2005.00541.x.
[38] Marsella R, Nicklin C, Lopez J. 2006. Studies on the role of routes of allergen exposure in high IgE-producing beagle dogs sensitized to house dust mites. Vet Dermatol. 17(5): 306–312.
[39] Olivry T, DeBoer DJ, Favrot C, Jackson HA, Mueller RS, Nuttall T, Prélaud P. 2010. International Task Force on Canine Atopic Dermatitis. Treatment of canine atopic dermatitis: 2010 clinical practice guidelines from the International Task Force on Canine Atopic Dermatitis. Vet Dermatol. 21(3): 233-48. DOI: 10.1111/j.1365-3164.2010.00889.x.
[40] Anturaniemi J, Zaldívar-López S, Savelkoul FJH, Elo K, Hielm-Björkman A. 2020. The effect of atopic dermatitis and diet on the skin transcriptome in staffordshire bull terriers. Frontiers in Veterinary Science. DOI: 10.3389/fvets.2020.552251.
[41] Masuda K, Sato A, Tanaka A, Kumagai A. 2020. Hydrolyzed diets may stimulate food-reactive lymphocytes in dogs. J Vet Med Sci. 82(2): 177-183. DOI: 10.1292/jvms.19-0222.
Published
2025-03-20
How to Cite
PrasetyoB. F., FirdausiZ. N., RahmadaniS. T., FadiaS. S., AdindaN., AmandaM., ZhengL. X., & NatawiriaM. S. L. (2025). Canine Atopic Dermatitis (CAD) di Rumah Sakit Hewan Pendidikan IPB University. Jurnal Veteriner Dan Biomedis, 3(1), 23-29. https://doi.org/10.29244/jvetbiomed.3.1.23-29.
Section
STUDI KASUS/ CASE STUDY
Copyright (c) 2025 Bayu Febram Prasetyo, Zalfaa Nurr Firdausi, Satria Tegar Rahmadani, Sindy Siti Fadia, Nada Adinda, Marsha Amanda, Lee Xiang Zheng, Maria Stella Linda Natawiria
This work is licensed under a Creative Commons Attribution 4.0 International License.
