Potensi Tanaman Alpukat (Persea americana Mill) dalam Bidang Dermatologi
Keywords:
Alpukat, Persea americana Mill, dermatologi
Abstract
Penggunaan obat tradisional yang berasal dari tanaman dapat menjadi alternatif untuk mengatasi masalah kulit. Tanaman alpukat (Persea americana Mill.) diketahui memiliki banyak khasiat karena mengandung flavonoid, saponin, tannin, alkaloid, steroid, dan fenol yang merupakan antioksidan yang berperan dalam menangkal radikal bebas, sehingga dapat digunakan sebagai alternatif terapi pada beberapa kelainan kulit, serta menjaga kualitas dan penampilan kulit. Metode yang digunakan oleh penulis adalah kajian literatur dari jurnal nasional maupun internasional. Artikel dan jurnal yang didapat dibaca, ditelaah dan dianalisis untuk memberikan informasi baru yang relevan. Hasil penelusuran didapatkan bahwa tanaman alpukat, baik dari daging buah, daun, biji dan kulit memiliki khasiat dalam bidang dermatologi, diantaranya yaitu sebagai antibakteri pada antijerawat, antijamur, tabir surya, agen pemutih, pelembab kulit, dan antiaging. Dapat disimpulkan bahwa tanaman alpukat dapat digunakan sebagai alternatif untuk mengatasi berbagai masalah kulit, walaupun masih harus dilakukan penelitian lebih lanjut untuk menggali lebih banyak manfaat lain dari tanaman alpukat dalam bidang dermatologi.
Kata kunci: Alpukat, Persea americana Mill, dermatologi.
References
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[17] Xie, Y., Yang, W., Tang, F., Chen, X. & Ren, L. (2015). Antibacterial activities of flavonoids: structure-activity relationship and mechanism. Current Medicinal Chemistry, 22(1), 132149.
[18] Miklasińska-Majdanik, M., Kępa, M., Wojtyczka, R.D., Idzik, D., & Wąsik, T.J. (2018). Phenolic compounds diminish antibiotic resistance of Staphylococcus aureus clinical strains. International Journal of Environmental Research And Public Health, 15, 2321.
[19] Widowati, R., Handayani, S. & Fikri, A.R.A. (2021). Phytochemical screening and antibacterial activities of Senggani (Melastoma malabathricum L.) ethanolic extract leaves. Jurnal Ilmu Pertanian Indonesia (JIPI), 26(4), 562568.
[20] Nofriyanti & Wildani. (2019). Formulasi krim dari ekstrak air daun alpukat (Persea americana Mill.) sebagai sediaan antijerawat. Jurnal Penelitian Farmasi Indonesia, 7(2), 51–56.
[21] Safitri, M., Zaky, M., & Chaerani, S. (2022). Pengembangan formulasi dan efektivitas sabun cair wajah ekstrak biji alpukat (Persea americana Mill) sebagai antijerawat terhadap bakteri Staphylococcus aureus. Jurnal Farmagazine, Vol. IX(1), 35-43.
[22] Widianti, R.A., Nofita, & Yasir, A.S. (2023). Formulasi sediaan salep ekstrak etanol daun alpukat (Persea americana Mill.) sebagai antiacne terhadap bakteri Staphylococcus aureus. Jurnal Ilmiah Wahana Pendidikan, 9(7), 722-732.
[23] Yuliandari, N., Rahayu. Y.P., Lubis, M.S. & Yuniarti, R. (2023). Uji aktivitas antibakteri formulasi sediaan gel antijerawat ekstrak etanol kulit buah alpukat (Persea americana Mill) terhadap bakteri Staphylococcus aureus. Journal of Pharmaceutical and Sciences, 6(4), 1960-1969.
[24] Yuliana, B., Suleman, A.W., Alyidrus, R., & Pratiwi, R.I. (2023). Formulasi dan uji aktivitas sediaan gel antijerawat ekstrak etanol daun alpukat (Persea americana Mill) terhadap Propionibacterium acne. Jurnal Ilmiah Jophus: Journal of Pharmacy UMUS, 4(02), 49-56.
[25] Chanyachailert, P., Leeyaphan, C., & Bunyaratavej, S. (2023). Cutaneous fungal infections caused by Dermatophytes and Non-Dermatophytes: an updated comprehensive review of epidemiology, clinical presentations, and diagnostic testing. Journal of Fungi, 9, 669.
[26] Mei, A., Ricciardo, B., Raby, E., & Kumarasinghe, S.P. (2022). Literature review. Plant-based therapies for dermatophyte infections. Tasman Medical Journal, 3, 21-37.
[27] Vitiello, A., Ferrara, F., Boccellino, M., Ponzo, A., Cimmino, C., Comberiati, E., Zovi, A., Clemente, S., & Sabbatucci, M. (2023). Antifungal drug resistance: an emergent health threat. Biomedicines, 11, 1063.
[28] Azizah, M., Akbar, P.T.A., & Hasanah, M. (2021). Uji aktivitas anti jamur ekstrak etanol biji alpukat (Persea americana Mill) terhadap jamur kulit Tricophyton rubrum ATCC 28188, Epidermophyton floccosum ATCC 50266 dan Micospprum canis ATCC 32699). Jurnal Kesehatan Saelmakers PERDANA, 4 (2), 177-179.
[29] Pandey, P., Sharma, A., Sharma, H., Vyas, G.K., & Sharma, M. (2023). Novel researched herbal sunscreen cream SPF determination by in-vitro model. Asian Journal of Pharmaceutical Research and Development, 11(2), 83-90.
[30] Bhattacharjee, D., Preethi, S., Patil, A.B., & Jain, V. (2021). A comparison of natural and synthetic sunscreen agents: a review. International Journal of Pharmaceutical Research, 13(1), 3494-3505.
[31] Aguilera, J., Gracia‐Cazaña, T. & Gilaberte, Y. (2023). New developments in sunscreens. Photochemical & Photobiological Sciences, 22, 2473–2482.
[32] Suhaenah, A., Widiastuti, H. & Arafat, M. (2019). Potensi ekstrak etanol biji alpukat (Persea americana Mill.) sebagai tabir surya. J Pharm Sci, 2(2), 88-94.
[33] Hwang, T., Lee, H.J., Park, W.S., Kang, D.M., Ahn, M.J., Yoon, H., Yoo, J.C., Moon, D.K. & Woo, D.K. (2022). Catechin-7-O-α-L-rhamnopyranoside can reduce α-MSH-induced melanogenesis in B16F10 melanoma cells through competitive inhibition of tyrosinase. Int J Med Sci, 19, 1131-1137.
[34] Goenka, S., & Toussaint, J. (2020). Citrate-coated platinum nanoparticles exhibit a primary particle-size dependent effect on stimulating melanogenesis in human melanocytes. Cosmetics, 7, 2-15.
[35] Laksmiani, N.P.L., Sanjaya, I.K.N. & Leliqia, N.P.E. (2020). The activity of avocado (Persea americana Mill.) seed extract containing catechin as skin lightening agent. Journal of Pharmacy & Pharamacognosy Research, 8(5), 449-456.
[36] Novasari, H., Pratiwi, A. & Mahmiara, N. (2021). Efektivitas formulasi sediaan lotion dari ekstrak etanol daun alpukat (Persea americana Mill.) sebagai pelembab kulit. Jurnal Farmasi, 3(2), 57-62.
[37] Henning, S.M., Guzman, J.B., Thames, G., Yang, J., Tseng, C.H., Heber, D., Kim, J. & Li, Z. (2022). Avocado consumption increased skin elasticity and firmness in women – a pilot study. Journal of Cosmetic Dermatology, 21(9), 4028-4034.
[2] Sunday, C.U., Ndidiamaka, H.O., Ugochukwu, D.D. & Njideka, I.A. (2022). Phytochemical analysis and antioxidant activity of avocado pear peel (Persea americana) extract. Journal of Pharmaceutical Research International, 34(28A), 22-29.
[3] Fernenda, L., Ramadhani, A.P. & Syukri, Y. (2022). Review : Aktivitas pegagan (Centella asiatica (L.) Urban) pada Kulit. (Review: Centella asiatica (L.) Urban activity in dermatology). Jurnal Sains Farmasi & Klinis, 9(3), 237–244.
[4] Badaring, D.R., Sari, S.P., Nurhabiba, S., Wulan, W. & Lembang, S.A. (2020). Uji ekstrak daun maja (Aegle marmelos L.) terhadap pertumbuhan bakteri Escherichia coli dan Staphylococcus aureus. IJFS, 6(1), 16-26.
[5] Ningsih, G., Fajrina, A., Husnunnisa. & Rivai, H. (2020). Overview of the botanical, phytochemical and antibacterial activity of the avocado plant (Persea americana Mill.). World Journal of Pharmacy and Pharmaceutical sciences, 9(11), 2602-2620.
[6] Bhuyan, D.J., Alsherbiny, M.A., Perera, S., Low, M., Basu, A., Devi, O.A., Barooah, M.S., Li, C.G. & Papoutsis, K. (2019). The Odyssey of bioactive compounds in avocado (Persea americana) and their health benefits. Antioxidant, 8, 426.
[7] Castro-López, C., Bautista-Hernández, I., González-Hernández, M.D., Martínez-Ávila, G.C., Rojas, R., Gutiérrez-Díez, A., Medina-Herrera, N. & Aguirre-Arzola, V.E. (2019). Polyphenolic profile and antioxidant activity of leaf purified hydroalcoholic extracts from seven Mexican Persea americina cultivars. Molecules, 24, 173.
[8] Kemit, N., Permana, I.D. & Kencana, P.K. (2019). Stabilitas senyawa flavonoid ekstrak daun alpukat (Persea americana Mill.) terhadap perlakuan pH dan suhu. Media Ilmu Teknologi Pangan, 6(1), 34-42.
[9] Abraham, J.D., Abraham, J. & Takrama, J.F. (2018). Morphological characteristics of avocado (Persea americana Mill.) in Ghana. African Journal of Plant Science, 12(4), 88-97.
[10] Bhore, S.J., Ochoa, D.S., Houssari, A.A., Zelaya, A.L., Yang, R., Chen, Z., Deeya, S.S., Sens, S.C.S., Schumann, M., Zhang, Z. & Eltantawy, E. (2021). Review: The avocado (Persea americana Mill.): A Review and sustainability perspectives. Preprints, 2021120523.
[11] Arukwe, U., Amadi, B., Duru, M.K., Agomuo, E., Adindu, E.A., Odika, P.C., Lele, K.C., Egejuru, L. & Anudike, J. (2012). Chemical composition of Persea americana leaf, fruit, and seed. IJJRAS, 11(2), 346-348.
[12] Ramos-Aguilar, A.L., Ornelas-Paz, J., Tapla-Vargas, L.M., Rulz-Cruz, S., Gardea-Bejar, A.A., Yahla, E.M., Ornelas-Paz, J.J., Pérez-Martínez, J.D., Rios-Velasco, C. & Ibarra-Junguera, V. (2019). The importance of the bioactive compounds of avocado fruit (Persea americana Mill) on human health. Biotecnia, 21(3), 154-162.
[13] Jimenez, P., Garcia, P., Quitral,V., Vasquez, K., Parra-Ruiz, C., Reyes-Farias, M., Garcia-Diaz, D.F., Robert, P., Encina, C. & Soto-Covasich, J. (2020). Pulp, leaf, peel and seed of avocado fruit: a review of bioactive compounds and healthy benefits. Food Reviews International, 37(6), 619-655.
[14] Tan, AU., Schlosser, B.J. & Paller, A.S. (2017). A review of diagnosis and treatment of acne in adult female patients. International Journal of Women's Dermatology, 4, 56–71.
[15] Sitohang, I.B.S., Fathan, H., Effendi, E. & Wahid, M. (2019). The susceptibility of pathogens associated with acne vulgaris to antibiotics. Med J Indones, 28, 21–7.
[16] Delost, G.R., Delost, M.E., Armile, J. & Lloyd, J. (2016). Staphylococcus aureus carriage rates and antibiotic resistance patterns in patients with acne vulgaris, J Am Acad Dermatol, 74(4), 673-678.
[17] Xie, Y., Yang, W., Tang, F., Chen, X. & Ren, L. (2015). Antibacterial activities of flavonoids: structure-activity relationship and mechanism. Current Medicinal Chemistry, 22(1), 132149.
[18] Miklasińska-Majdanik, M., Kępa, M., Wojtyczka, R.D., Idzik, D., & Wąsik, T.J. (2018). Phenolic compounds diminish antibiotic resistance of Staphylococcus aureus clinical strains. International Journal of Environmental Research And Public Health, 15, 2321.
[19] Widowati, R., Handayani, S. & Fikri, A.R.A. (2021). Phytochemical screening and antibacterial activities of Senggani (Melastoma malabathricum L.) ethanolic extract leaves. Jurnal Ilmu Pertanian Indonesia (JIPI), 26(4), 562568.
[20] Nofriyanti & Wildani. (2019). Formulasi krim dari ekstrak air daun alpukat (Persea americana Mill.) sebagai sediaan antijerawat. Jurnal Penelitian Farmasi Indonesia, 7(2), 51–56.
[21] Safitri, M., Zaky, M., & Chaerani, S. (2022). Pengembangan formulasi dan efektivitas sabun cair wajah ekstrak biji alpukat (Persea americana Mill) sebagai antijerawat terhadap bakteri Staphylococcus aureus. Jurnal Farmagazine, Vol. IX(1), 35-43.
[22] Widianti, R.A., Nofita, & Yasir, A.S. (2023). Formulasi sediaan salep ekstrak etanol daun alpukat (Persea americana Mill.) sebagai antiacne terhadap bakteri Staphylococcus aureus. Jurnal Ilmiah Wahana Pendidikan, 9(7), 722-732.
[23] Yuliandari, N., Rahayu. Y.P., Lubis, M.S. & Yuniarti, R. (2023). Uji aktivitas antibakteri formulasi sediaan gel antijerawat ekstrak etanol kulit buah alpukat (Persea americana Mill) terhadap bakteri Staphylococcus aureus. Journal of Pharmaceutical and Sciences, 6(4), 1960-1969.
[24] Yuliana, B., Suleman, A.W., Alyidrus, R., & Pratiwi, R.I. (2023). Formulasi dan uji aktivitas sediaan gel antijerawat ekstrak etanol daun alpukat (Persea americana Mill) terhadap Propionibacterium acne. Jurnal Ilmiah Jophus: Journal of Pharmacy UMUS, 4(02), 49-56.
[25] Chanyachailert, P., Leeyaphan, C., & Bunyaratavej, S. (2023). Cutaneous fungal infections caused by Dermatophytes and Non-Dermatophytes: an updated comprehensive review of epidemiology, clinical presentations, and diagnostic testing. Journal of Fungi, 9, 669.
[26] Mei, A., Ricciardo, B., Raby, E., & Kumarasinghe, S.P. (2022). Literature review. Plant-based therapies for dermatophyte infections. Tasman Medical Journal, 3, 21-37.
[27] Vitiello, A., Ferrara, F., Boccellino, M., Ponzo, A., Cimmino, C., Comberiati, E., Zovi, A., Clemente, S., & Sabbatucci, M. (2023). Antifungal drug resistance: an emergent health threat. Biomedicines, 11, 1063.
[28] Azizah, M., Akbar, P.T.A., & Hasanah, M. (2021). Uji aktivitas anti jamur ekstrak etanol biji alpukat (Persea americana Mill) terhadap jamur kulit Tricophyton rubrum ATCC 28188, Epidermophyton floccosum ATCC 50266 dan Micospprum canis ATCC 32699). Jurnal Kesehatan Saelmakers PERDANA, 4 (2), 177-179.
[29] Pandey, P., Sharma, A., Sharma, H., Vyas, G.K., & Sharma, M. (2023). Novel researched herbal sunscreen cream SPF determination by in-vitro model. Asian Journal of Pharmaceutical Research and Development, 11(2), 83-90.
[30] Bhattacharjee, D., Preethi, S., Patil, A.B., & Jain, V. (2021). A comparison of natural and synthetic sunscreen agents: a review. International Journal of Pharmaceutical Research, 13(1), 3494-3505.
[31] Aguilera, J., Gracia‐Cazaña, T. & Gilaberte, Y. (2023). New developments in sunscreens. Photochemical & Photobiological Sciences, 22, 2473–2482.
[32] Suhaenah, A., Widiastuti, H. & Arafat, M. (2019). Potensi ekstrak etanol biji alpukat (Persea americana Mill.) sebagai tabir surya. J Pharm Sci, 2(2), 88-94.
[33] Hwang, T., Lee, H.J., Park, W.S., Kang, D.M., Ahn, M.J., Yoon, H., Yoo, J.C., Moon, D.K. & Woo, D.K. (2022). Catechin-7-O-α-L-rhamnopyranoside can reduce α-MSH-induced melanogenesis in B16F10 melanoma cells through competitive inhibition of tyrosinase. Int J Med Sci, 19, 1131-1137.
[34] Goenka, S., & Toussaint, J. (2020). Citrate-coated platinum nanoparticles exhibit a primary particle-size dependent effect on stimulating melanogenesis in human melanocytes. Cosmetics, 7, 2-15.
[35] Laksmiani, N.P.L., Sanjaya, I.K.N. & Leliqia, N.P.E. (2020). The activity of avocado (Persea americana Mill.) seed extract containing catechin as skin lightening agent. Journal of Pharmacy & Pharamacognosy Research, 8(5), 449-456.
[36] Novasari, H., Pratiwi, A. & Mahmiara, N. (2021). Efektivitas formulasi sediaan lotion dari ekstrak etanol daun alpukat (Persea americana Mill.) sebagai pelembab kulit. Jurnal Farmasi, 3(2), 57-62.
[37] Henning, S.M., Guzman, J.B., Thames, G., Yang, J., Tseng, C.H., Heber, D., Kim, J. & Li, Z. (2022). Avocado consumption increased skin elasticity and firmness in women – a pilot study. Journal of Cosmetic Dermatology, 21(9), 4028-4034.
Published
2024-09-30
How to Cite
SebayangS., RayendraR., WientarsihI., & PriosoeryantoB. P. (2024). Potensi Tanaman Alpukat (Persea americana Mill) dalam Bidang Dermatologi. Jurnal Veteriner Dan Biomedis, 2(2), 79-85. https://doi.org/10.29244/jvetbiomed.2.2.79-85.
Section
PENELITIAN/ RESEARCH
Copyright (c) 2024 Shalina Sebayang
This work is licensed under a Creative Commons Attribution 4.0 International License.
