Immune mediated haemolytic anemia pada anjing siberian husky

  • . Loisa Klinik Hewan Drh Loisa
  • Nur Fitria Anggraini Klinik Hewan Drh Loisa
  • Talitha Khairunisa Klinik Hewan Drh Loisa
  • Novri Wandi Bahar Klinik Hewan Drh Loisa
DOI: https://doi.org/10.29244/avl.2.2.29-30
Keywords: Immune Mediated Haemolytic Anemia (IMHA), Babesia sp., Spherocyte

Abstract

Immune Mediated Haemolytic Anemia (IMHA) merupakan anemia yang muncul akibat hemolisis eritrosit di dalam pembuluh darah yang berhubungan dengan mediator sistem imun. Salah satu penyebab kondisi IMHA yaitu keberadaan parasit darah (Babesia sp.) dengan vektor caplak (Rhipicephalus sanguineus). Diagnosa IMHA yang disebabkan oleh infeksi Babesia sp pada anjing kasus ini terlihat melalui pemeriksaan sitologi dengan ditemukannya spherocyte dan terjadi hemolisis intravaskular sehingga masuk dalam kategori secondary IMHA. Pemeriksaan fisik di abdomen bagian kanan teraba adanya massa keras dan dilanjutkan pemeriksaan ultrasonografi dan radiografi. Hasil pemeriksaan ultrasonografi ditemukan adanya hepatomegali dan splenomegali.  Hasil radiografi bagian thoraks tampak adanya tromboemboli di paru-paru, sedangkan pada bagian abdomen menunjukkan adanya internal bleeding.  Berdasarkan hasil pemeriksaan darah menunjukkan rendahnya MCV dan MCHC (anemia mikrositik hipokromik oleh hemolisis), serta peningkatan RBC yang disebabkan oleh produksi RBC (eritrogenesis) khususnya retikulosit. Infeksi Babesia sp. pada anjing ini tampak pada tingginya persentase granulosit.  Kejadian IMHA merupakan kondisi kronis, sehingga untuk mencegah IMHA diperlukan edukasi secara menyeluruh mengenai bahaya dampak infeksi ektoparasit (tick dan fleas) dalam jangka panjang dan cara mengendalikan ektoparasit.

Downloads

Download data is not yet available.

References

Balch A, Mackin. 2007. Canine immune-mediated hemolytic anemia: patophysiology, clinical signs, and diagnosis. Compend Contin Educ Vet. 29(4):217-225.

Carr AP, Panciera DL, Kidd L. 2002. Prognostic factor for mortality and thromboembolism in canine immune-mediated hemolytic anemia: a retrospective study of 72 dogs. J Vet Intern Med. 16:504-509.

Day MJ. 2012. Canine-immunomediated hemolytic anemia. NAVC Clinician’s Brief. October: 53-57.

Mackin A. 2014. Immune-mediated hemolytic anemia: pathophysiology and diagnosis. DVAVM: Mississippi University. http://www.delawarevalleyacademyvm.org/pdfs/oct14/Autoimmune.pdf

Sharp C, Kerl ME. 2008.Standard of Care Emergency and Critical Care Management: Immune Mediated-Hemolytic Anemia. 10(10): 1-6. http://studyres.com/doc/7841642/immune-mediated-hemolytic-anemia

Stone M. 2010. Ettinger: Textbook of Veterinary Internal Medicine-Immune Mediated Hemolytic Anemia and Immune Mediated Thrombocytopenia. 7th Ed. Saunders: Elsevier.

Published
2018-05-02
How to Cite
Loisa., AnggrainiN. F., KhairunisaT., & BaharN. W. (2018). Immune mediated haemolytic anemia pada anjing siberian husky. ARSHI Veterinary Letters, 2(2), 29-30. https://doi.org/10.29244/avl.2.2.29-30
Issue
Vol. 2 No. 2 (2018): ARSHI Veterinary Letters - Mei 2018
Section
Case Study

Copyright (c) 2018 CC-BY-SA

Creative Commons License

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Authors who publish with this journal agree to the following terms:

1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).

##plugins.generic.relatedArticle.noArticleFound##