FORMULATION OF KONJAC GLUCOMANNAN AND CARRAGEENAN-BASED HARD CAPSULE

Authors

  • Winda Herman Agroindustrial Engineering Study Program, Faculty of Agricultural Engineering & Technology, IPB University
  • Titi Candra Sunarti Agroindustrial Engineering Study Program, Faculty of Agricultural Engineering & Technology, IPB University
  • Sapta Raharja Agroindustrial Engineering Study Program, Faculty of Agricultural Engineering & Technology, IPB University
  • Khaswar Syamsu Agroindustrial Engineering Study Program, Faculty of Agricultural Engineering & Technology, IPB University

DOI:

https://doi.org/10.24961/j.tek.ind.pert.2026.36.1.1

Abstract

Commercial hard capsules are primarily manufactured from bovine or porcine gelatin, which often restricts consumer choice owing  to religious concerns and vegetarian lifestyles. Konjac glucomannan demonstrates superiority as a gelling and film-forming material, making it a highly potential gelatin substitute in the manufacture of hard capsules. This study employed response surface methodology (RSM) to design and determine the optimum conditions for a hard capsule formula based on konjac glucomannan and carrageenan. The independent variables analyzed were the ratios of konjac glucomannan (2.5%, 3%, and 3.5%; X1), carrageenan (1.5%, 2.0%, and 2.5%; X2), and glycerol (0, 0.125%, and 0.250%; X3). The dependent response variables analyzed were capsule moisture content and disintegration time. The moisture content ranged from 5.6% to 15.9%, indicating that higher ratios of konjac glucomannan and glycerol resulted in higher capsule moisture content. Capsule disintegration time ranged from 10.12 to 24.25 min, indicating that a higher glycerol ratio accelerated the hard capsule destruction time. Both the capsule moisture content and disintegration time were significantly influenced by the raw material used and the resulting capsule specifications.

Keywords: carrageenan, formula optimization, hard capsule, konjac glucomannan

Author Biographies

  • Winda Herman, Agroindustrial Engineering Study Program, Faculty of Agricultural Engineering & Technology, IPB University

    .

  • Titi Candra Sunarti, Agroindustrial Engineering Study Program, Faculty of Agricultural Engineering & Technology, IPB University

    .

  • Khaswar Syamsu, Agroindustrial Engineering Study Program, Faculty of Agricultural Engineering & Technology, IPB University

    .

References

Ahmad A, Rehman MU, Wali AF, El-Serehy HA, Al-Misned FA, Maodaa SN, Aljawdah HM, Mir TM, Ahmad P. 2020. Box-Behnken Response Surface Design Of Polysaccharide Extraction From Rhododendron Arboreum And The Evaluation Of Its Antioxidant Potential. Molecules. 25 (17);01-12.
Amalina N, Yuni A, Estu M D. 2020. Formulasi Cangkang Kapsul dengan Kombinasi Kappa Karagenan dan Iota Karagenan. Pharmaceutical and Biomedical Sciences Journal. Volume 2 (1), 2020, 1-10
Chen Y, Zhao H, Liu X, Li Z, Liu B, Wu J, Shi M, Norde W, Li Y. 2016. TEMPO-oxidized Konjac glucomannan as appliance for the preparation of hard capsules. Carbohydr Polym. 143:262–269. doi:10.1016/j.carbpol.2016.01.072.
Fahrullah, Mohamad E. 2022. Karakterisasi mikrostruktur film whey dengan penambahan konjac glukomannan. Jurnal Agrointek 16 (3): 396-404
Future Market Insights. 2021. Hard gelatin capsules market. https://www.futuremarketinsights.com/reports/hard-gelatin-capsules-market.
Gea, T. 2011. Pembuatan Kapsul Alginat Yang Mengandung Titanium Dioksida Dan Pengujian Sifat-Sifat Fisiknya.
Gelatin Representatives of the Word. 2021. Gelatin. https://www.gelatininfo.com/grow.html.
Gu L, McClements DJ, Li Jiaying, Su Y, Yang Y, Li Junhua. 2021. Formulation of alginate/carrageenan microgels to encapsulate, protect and release immunoglobulins: Egg Yolk IgY. Food Hydrocoll. 112 September 2020:106349. doi:10.1016/j.foodhyd.2020.106349.
Julianto, Kiki H, Ine M. 2013. Karakteristik Cangkang Kapsul Yang Terbuat Dari Gelatin Tulang Ikan. Jurnal Akuatika 4 (1) : 45-54.
Karim AA, Bhat R. 2009. Fish gelatin: properties, challenges, and prospects as an alternative to mammalian gelatins. Food Hydrocoll. 23(3):563–576. doi:10.1016/j.foodhyd.2008.07.002.
Kementerian Kesehatan Republik Indonesia. 2020. Farmakope Indonesia Edisi VI. Jakarta.
Mahardika M, Dariyat, Ninik TS, Fauzan A. 2022. Sintesis dan Karakterisasi Cangkang Kapsul Non Gelatin Dari Lidah Buaya (Aloe Vera L.) Karagenan. Jurnal Medika & Sains 2 (2) : 76-88.
Rachmawati W. 2018. Konjac Glucomannan-Agar-Gliserin for Biopolimer of Hard Capsule.Tesis Institut Teknologi Sepuluh November.Surabaya
Suptijah P, Sugeng HS, Kurniawati. 2012. Aplikasi Karagenan Sebagai Cangkang Kapsul Keras Alternatif Pengganti Kapsul Gelatin. Jurnal Pengolahan Hasil Perikanan Indonesia 15 (3) : 223-231.

Downloads

Published

2026-04-20

How to Cite

FORMULATION OF KONJAC GLUCOMANNAN AND CARRAGEENAN-BASED HARD CAPSULE. (2026). Jurnal Teknologi Industri Pertanian, 36(1), 1-11. https://doi.org/10.24961/j.tek.ind.pert.2026.36.1.1