Profil Darah dan Temuan Histopatologi Ikan Mas (Cyprinus carpio) yang Termanifestasi Parasit Myxozoa sp.
DOI:
https://doi.org/10.29244/jvetbiomed.3.2.%25p.Keywords:
Histopatologi, Ikan mas, Myxozoa sp, Profil darahAbstract
Manifestasi parasit merupakan salah satu faktor yang dapat menyebabkan penurunan tingkat kesehatan ikan. Parasit seperti Myxozoa sp. mengakibatkan gangguan pernapasan, abnormalitas cara berenang, hingga kongesti, dan perubahan warna insang menjadi pusat pada ikan mas karena menyerang kulit, insang, hingga organ internal ikan. Seekor ikan mas dengan berat badan 272,07 gram dan panjang tubuh 25,5 cm menunjukkan gejala klinis terlihat berenang di dasar kolam dengan pergerakan yang kurang aktif. Ikan tersebut selanjutnya dilakukan pemeriksaan di Laboratorium Patologi Balai Pemeriksaan Kesehatan Ikan dan Lingkungan Serang. Pemeriksaan meliputi pemeriksaan parasit, ulas darah, perhitungan hematokrit, hemoglobin, sel darah merah dan sel darah putih, diferensial leukosit, serta pemeriksaan patologi yang terdiri dari nekropsi dan pengamatan preparat histopatologi. Hasil pemeriksaan menunjukkan ikan mas mengalami manifestasi parasit Myxozoa sp. disertai temuan parasit Dactylogyrus sp. Profil darah menunjukkan adanya kelainan pada nilai hemoglobin dan sel darah putih. Abnormalitas histopatologi terlihat pada organ insang, hati, limpa, ginjal, dan usus.
References
[1] Kementerian Kelautan dan Perikanan (KKP). 2024. Laporan Kinerja Tahun 2024. https://www.kkp.go.id/download-pdf-akuntabilitas-kinerja/akuntabilitas-kinerja-pelaporan-kinerja-laporan-kinerja-direktorat-ikan-air-payau-tahun-2024.pdf
[2] Banu H, & Rathinam RB. 2023. Myxozoan fish diseases: Possible treatment and zoonoses. Journal of Parasitic Diseases. 47(2): 215–223. https://doi.org/10.1007/s12639-023-01496-9
[3] Witeska M, Kondera E, Ługowska K, & Bojarski B. 2022. Hematological methods in fish – Not only for beginners. Aquaculture. 547: 737498. https://doi.org/10.1016/j.aquaculture.2021.737498
[4] Rašković B, & Berillis P. 2022. Special Issue on the Histopathology of aquatic animals. Applied Sciences. 12(3): 971.
[5] Wahab A, Zahid M, Jawad M, Saeed F, Khan I, & Rizwan, A. 2021. Distribution of two monogeneans (Dactylogyrus Vastator & Gyrodactylus) in fish fauna of Barganatu Dam. FR Bannu. KPK. Pakistan.
[6] Chaudhary A, Chiary HR, & Singh HS. 2017. First molecular confirmation of the Dactylogyrus anchoratus and D. vastator (Monogenea, Dactylogyridae) from Carassius auratus in western India. BioInvasions Records. 6(1): 79-85.
[7] Benovics M, Nejat F, Abdoli A, & Šimková A. 2021. Molecular and morphological phylogeny of host-specific Dactylogyrus parasites (Monogenea) sheds new light on the puzzling Middle Eastern origin of European and African lineages. Parasites & Vectors. 14: 1-15.
[8] Al-Hasyimia US, Dewi NK, & Pribadi TA. 2016. Identifikasi ektoparasit pada ikan lele sangkuriang (Clarias gariepinus) yang dibudidayakan di Balai Benih Ikan (BBI) Boja Kendal. Life science. 5(2): 118-124.
[9] Pujiastuti, N, & Setiati N. 2015. Identifikasi dan prevalensi ektoparasit pada ikan konsumsi di Balai Benih Ikan Siwarak. Life Science. 4(1).
[10] Clauss TM, Dove AD, & Arnold JE. 2008. Hematologic disorders of fish. Veterinary clinics of North America: Exotic animal practice. 11(3): 445-462.
[11] Al–Khayat AS. 2020. Hematological study to evaluate the Cyprinus carpio fish healthy in two areas of Baghdad city. Ann. Trop. Med. Pub. Hlth. 23(4): 169-176.
[12] Effendi I, Farhana H, Mardalisa M, Yoswaty D, Syawal H, Austin B, & Kurniawan R. 2025. Phytoimmunostimulants increase of the immunity of common carp (Cyprinus carpio) against Aeromonas hydrophila infection in brackish water. AACL Bioflux. 18(1): 277-284.
[13] Yanto H, Hasan H, & Sunarto. 2015. Kajian kadar hemoglobin dan hematokrit ikan mas (Cyprinus carpio) yang dipelihara di kolam. Jurnal Akuakultur Indonesia. 14(1): 11–20. https://doi.org/10.19027/jai.14.1.11-20
[14] Rosidah AR, Rustikawati I, & Octavia F. 2018. The effect of differences in altitude location of an aquaculture on fish’s hematocrit and fish’s haemoglobin of Carp fish and resistance to bacterial attack. Earth and Environmental Science. 137(1): 1-9.
[15] Sanoesi E. 2020. Hematological analysis of common carp (Cyprinus carpio) using hematology analyzer tools and manual at fish seed center, Pasuruan, East Java. IOP Conference Series: Earth and Environmental Science. 493: 012011. https://doi.org/10.1088/1755-1315/493/1/012011
[16] Witeska M, Kondera E, & Bojarski B. 2023. Hematological and hematopoietic analysis in fish toxicology:A review. Animals. 13(16): 2625. https://doi.org/10.3390/ani13162625
[17] Rosmanah L, Nugraha AB, & Darusman, HS. 2022. Leukocyte Differential Study in Macaca nemestrina infected by Plasmodium spp. Indonesian Journal of Primatology. 1(01): 10-14.
[18] Smith SA, Newman SJ, Coleman MP, & Alex C. 2018. Characterization of the histologic appearance of normal gill tissue using special staining techniques. Journal of Veterinary Diagnostic Investigation 30(5): 688-698.
[19] Guo Q, Huang M, Liu Y, Zhang X, & Gu Z. 2018. Morphological plasticity in Myxobolus Bütschli, 1882: a taxonomic dilemma case and renaming of a parasite species of the common carp. Parasites & Vectors. 11: 1-11.
[20] Rajini A, Revathy K, & Selvam G. 2015. Histopathological changes in tissues of Danio rerio exposed to sub lethal concentration of combination pesticide. Indian Journal of Science and Technology. 8(18): 1-12.
[21] Fadilla L, Puspawati N, & Nugroho RB. 2020. Identifikasi Salmonella Sp dan Gambaran Histopatologi Hati Ayam yang Terinfeksi Salmonella di Pasar Tradisional Kota Boyolali. In Conference on Innovation in Health, Accounting and Management Sciences. 1: 10-15.
[22] Khan MS, Javed M, Rehman MT, Urooj M, & Ahmad MI. 2020. Heavy metal pollution and risk assessment by the battery of toxicity tests. Scientific Reports. 10(1): 16593.
[23] Elias NS, Abouelghar GE, Sobhy HM, Elmeniawy HF, & Elsaiedy EG. 2020. Sublethal effects of the herbicide thiobencarb on fecundity, histopathological and biochemical changes in the African catfish (Clarias gariepinus). Iranian Journal of Fisheries Sciences. 19(3): 1589-1614.
[24] Steinel NC, & Bolnick DI. 2017. Melanomacrophage centers as a histological indicator of immune function in fish and other poikilotherms. Frontiers in Immunology. 8: 827. https://doi.org/10.3389/fimmu.2017.00827
[25] Nowak BF, Dang M, Webber C, Neumann L, Bridle A, Bermudez R, & Evans D. 2021. Changes in the splenic melanomacrophage centre surface area in southern bluefin tuna (Thunnus maccoyii) are associated with blood fluke infections. Pathogens. 10(1): 79.
[26] Agius C, & Roberts RJ. 2003. Melano‐macrophage centres and their role in fish pathology. Journal of fish diseases. 26(9): 499-509.
[27] Manrique WG, Figueiredo MAP, Charlie-Silva I, de Andrade Belo MA, & Dib CC. 2019. Spleen melanomacrophage centers response of Nile tilapia during Aeromanas hydrophila and Mycobacterium marinum infections. Fish & shellfish immunology. 95: 514-518.
[28] Kaewamatawong T, Rattanapinyopituk K, Ponpornpisit A, Pirarat N, Ruangwises S, & Rungsipipat A. 2013. Short-term exposure of Nile Tilapia (Oreochromis niloticus) to mercury: histopathological changes, mercury bioaccumulation, and protective role of metallothioneins in different exposure routes. Toxicologic pathology. 41(3): 470-479.
[29] Magouz FI, El-Din MTS, Amer AA, Gewaily MS, El-Dahdoh WA, & Dawood MA. 2022. A blend of herbal essential oils enhanced the growth performance, blood bio-immunology traits, and intestinal health of Nile tilapia (Oreochromis niloticus). Annals of Animal Science. 22(2): 751-761.
[30] Purba SD, Tana S, & Saraswati TR. 2021. Pengaruh Air Rendaman Batang Balimo (Zanthoxylum nitidum) terhadap Histologis Ginjal Tikus Putih (Rattus norvegicus) Setelah Diberi Ciu. Buletin Anatomi dan Fisiologi. 6(1): 7-16.
[31] Charmi A, Bahmani M, Sajjadi MM, & Kazemi R. 2009. Morpho-histological study of kidney in farmed juvenile beluga, Huso huso (Linnaeus, 1758). Pakistan Journal of Biological Sciences. 12(1): 11-18.
[32] Eroschenko, & Victor P. 2013. diFIORE'S Atlas of Histology with Functional Correlations. 12th ed. Baltimore: Wolters Kluwer Health
[33] Ritchie JM. 2012. Inflammation and disintegration of intestinal villi in an experimental model for Vibrio parahaemolyticus-induced diarrhea. PLoS Pathogens. 8(3): e1002593. https://doi.org/10.1371/journal.ppat.1002593
[34] Bakke-McKellep AM, Penn MH, Salas PM, Refstie S, Sperstad S, Landsverk T, & Krogdahl Å. 2007. Effects of dietary soyabean meal, inulin and oxytetracycline on intestinal microbiota and epithelial cell stress, apoptosis and proliferation in the teleost Atlantic salmon (Salmo salar L.). British Journal of Nutrition. 97(4): 699-713.
[35] Ayunin Q, & Pi S. 2019. Identification of bacteria and parasites on semi-intensive culture of catfish (Pangasius sp.). Journal of Aquaculture and Fish Health. 9(2): 131–139.
[36] Maor-Landaw K. 2022. Infection by the parasite Myxobolus bejeranoi suppresses the immune system of hybrid tilapia. Microorganisms. 10(10): 1893. https://doi.org/10.3390/microorganisms10101893
[37] Ringø E. 2004. Damaging effect of the fish pathogen Aeromonas salmonicida ssp. salmonicida on intestinal enterocytes of Atlantic salmon (Salmo salar L.). Cell and Tissue Research. 318: 305–311. https://doi.org/10.1007/s00441-004-0972-3
[38] Stilwell J, & Yanong R. 2024. Myxosporidiosis (Myxozoan Infections) in Warmwater Fish. University of Florida. https://edis.ifas.ufl.edu/publication/FA201
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Copyright (c) 2025 Adik Sandia Santosa Asmali, Dhea Putri Ghinayatul Ilmi, Alya Nur Mahdani, Jasmine Marcella Cassandra Gunawan, Joko Suwiryono, Ratna Amalia Kurniasih, Tyagita Hartady
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