Canine monocytic Ehrlichiosis in Alaskan Malamute dog in GloriaVet Pet Health Solution, Bandung, Indonesia

Aqila Zata Amani; Kinanti Dwi Rahma; Aryani Sismin Satyaningtijas; Ivan Satriawan; Nurul Nadelia; Sus Derthi Widhyari

doi:10.29244/currbiomed.4.1.24

Authors

Aqila Zata Amani Study Program of Veterinary Profession Education, School of Veterinary Medicine and Biomedical Sciences, IPB University, Bogor, Indonesia
Kinanti Dwi Rahma Study Program of Veterinary Medicine, School of Veterinary Medicine and Biomedical Sciences, IPB University, Bogor, Indonesia
Aryani Sismin Satyaningtijas Division of Physiology, School of Veterinary Medicine and Biomedical Sciences, IPB University, Bogor, Indonesia https://orcid.org/0000-0002-3863-7555
Ivan Satriawan GloriaVet Pet Health Solution, Bandung, Indonesia
Nurul Nadelia GloriaVet Pet Health Solution, Bandung, Indonesia
Sus Derthi Widhyari Division of Internal Medicine, School of Veterinary Medicine and Biomedical Sciences, IPB University, Bogor, Indonesia https://orcid.org/0000-0003-3030-9482

DOI:

https://doi.org/10.29244/currbiomed.4.1.24

Keywords:

blood transfusion, crossmatch, dog, Ehrlichiosis, clinical manifestation

Abstract

Background Ehrlichiosis is an infection caused by the bacterium Ehrlichia canis, which attacks monocytes. Ehrlichiosis is characterized by anemia, lethargy, lameness, pancytopenia, hemorrhage, and weight loss.

Objective This study aimed to describe the clinical findings and treatment of a dog diagnosed with Ehrlichia canis infection.

Case A 5-year-old female Alaskan Malamute dog named Salt was brought to the clinic of GloriaVet Pet Health Solution, Bandung, Indonesia, with lameness and weakness, accompanied by high fever and very pale mucous membranes (pallor).

Examination and treatments Dog was examined using a general examination, hematology test, biochemistry test, native smear, and IDExx SNAP^© 4dx test kit. The examinations showed a positive result for Ehrlichia canis infection, along with severe pancytopenia, hyperglobulinemia, and thrombocytopenia. Diagnosis heavily relied on serology and clinical manifestation, and further PCR testing was not performed. The treatment consisted of doxycycline 10 mg/kg/day for 28 days, a 0.75% ketamine drip infusion, darbepoetin alfa, and a blood transfusion.

Conclusion Dog was infected with chronic ehrlichiosis with several clinical symptoms including severe anemia. Treatment with doxycycline as the treatment of choice for ehrlichiosis infection and a blood transfusion for treating severe anemia showed signs of improvement, but were ultimately ineffective due to the poor prognosis associated with chronic ehrlichiosis and severe pancytopenia.