Intracellular Ca2+ Regulation in Calcium Sensitive Phenotype of Saccharomyces cerevisiae

. HERMANSYAH

doi:10.4308/hjb.17.1.1

Intracellular Ca2+ Regulation in Calcium Sensitive Phenotype of Saccharomyces cerevisiae

. HERMANSYAH Sriwijaya University

Abstract

Intracellular cytosolic Ca2+ concentration accumulation plays an essential information in Saccharomyces cerevisiae i.e. to explain cellular mechanism of Ca2+ sensitive phenotype. Disruption both S. cerevisiae PPase PTP2 and MSG5 genes showed an inhibited growth in the presence of Ca2+. On the other hand, by using Luminocounter with apoaequorin system, a method based upon luminescent photoprotein aequorin, intracellular Ca2+ concentration was accumulated as a consequence of calcium sensitive phenotype of S. cerevisiae. This fact indicated that PPase ptp2D and msg5D were involved in intracellular Ca2+ transport in addition their already known pathways i.e Mitogen Activated Protein Kinase cell wall integrity pathway, high osmolarity glycerol (HOG) pathway, and pheromone response FUS3 pathway.

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How to Cite

HERMANSYAH. (1). Intracellular Ca2+ Regulation in Calcium Sensitive Phenotype of Saccharomyces cerevisiae. HAYATI Journal of Biosciences, 17(1), 1. https://doi.org/10.4308/hjb.17.1.1

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Vol. 17 No. 1 (2010): March 2010

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Articles

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