https://journal.ipb.ac.id/index.php/cbj <p><img style="float: left; padding: 0px 8px 8px 0px;" src="/public/site/images/admincbj/cover_homepage1.jpg" alt=""></p> <div style="text-align: justify; line-height: 19px!important; font: normal 16px 'Roboto', sans-serif!important;">Current Biochemistry (CB) (<a href="https://issn.brin.go.id/terbit/detail/1399256510" target="_blank" rel="noopener">e-ISSN : 2355-7931</a> ; <a href="https://issn.brin.go.id/terbit/detail/1398964790" target="_blank" rel="noopener">p-ISSN : 2355-7877</a>)&nbsp;publishes the results of original research that contribute significantly to the understanding of the chemical compound and reaction that occur within living organism. Preference will be accorded to manuscripts that develop new concepts or experimantal approaches, particularly in the advancing areas of biochemistry science. Manuscripts that are primarily theoretical in nature or in the field of bioinformatics must be directed toward explaining important results previously not understood, making important predictions that can be experimentally tested, or developing segnificant advances in theory of general interest to biochemists. Submission of manuscripts in emerging areas in biochemistry, chemical biology, biophysics, proteomics, model studies and structures, cellular and molecular biology, computational biochemistry, biotechnology, and new methods development is encouraged especially if they address basic biochemical mechanisms.<br><br>Manuscripts should be written and published in Bahasa or English and should be submitted to CB. Authors should refer to the guidline below when preparing their manuscripts. Previously published manuscripts (either in whole or in part) will not be considered.&nbsp;</div> en-US imart171@yahoo.com (Prof. Dr. Ir. I Made Artika, M.App.Sc) husnawati@apps.ipb.ac.id (Husnawati) Sat, 06 Jul 2024 10:45:18 +0700 OJS 3.1.2.4 http://blogs.law.harvard.edu/tech/rss 60 https://journal.ipb.ac.id/index.php/cbj/article/view/55424 <p>Penelitian terhadap pemanfaatan salak khususnya salak Sidempuan sebagai inhibitor α-glukosidase belum dilakukan. Penelitian ini bertujuan mengukur kadar proksimat (air, abu, protein kasar, lemak kasar, serat kasar, dan karbohidrat), menganalisis komponen fitokimia, kandungan total fenolik dan aktivitas penghambatan α-glukosidase pada ekstrak air dan etanol daging buah salak Sidempuan. Kadar total fenol diukur menggunakan metode Folin Ciocalteu. Aktivitas penghambatan α-glukosidase diukur menggunakan substrat pNPG. Kadar karbohidrat, air, abu, lemak kasar, protein kasar, dan serat kasar berturut-turut sebesar 86.35%, 6.57%, 3.60%, 1.44%, 1.24%, dan 0.82%. Kedua ekstrak mengandung senyawa flavonoid dan saponin. Ekstrak etanol 70% daging buah salak Sidempuan memiliki kandungan total fenol sebesar 10.6 mg GAE/g ekstrak, lebih tinggi dibandingkan ekstrak air sebesar 5.55 mg GAE/g esktrak. Ekstrak etanol daging buah salak Sidempuan memiliki konsentrasi inhibisi (IC₅₀) sebesar 13.69 mg/L. Konsentrasi ini lebih kecil dibandingkan ekstrak air yaitu 4160.56 mg/L, namun masih lebih besar dibandingkan akarbosa yaitu 1.15x10-3 mg/L sebagai kontrol positif.</p> Mega Safithri, Aprilita Putri Defan Ritonga, Susi Indariani, Maheswari Alfira Dwicesaria, Sulistiyani, Hasim Copyright (c) 2024 Mega Safithri, Aprilita Putri Defan Ritonga, Susi Indariani, Maheswari Alfira Dwicesaria, Sulistiyani, Hasim https://creativecommons.org/licenses/by-sa/4.0 https://journal.ipb.ac.id/index.php/cbj/article/view/55424 Sat, 06 Jul 2024 10:45:59 +0700