@article{Poetri_Soejoedono_1, title={PRODUKSI ANTIBODI KUNING TELUR (IgY) ANTI STREPTOCOCCUS MUTANS SEBAGAI ANTI KARIES GIGI}, volume={11}, url={https://journal.ipb.ac.id/index.php/JIPI/article/view/13906}, abstractNote={<p>The aim of this study was to explore IgY anti <em>Streptococcus mutan</em> production and the ability of Igy <em>Streptococcus</em> <em>mutans</em> blocking adhesion process. The eggs was collected from Single Comb Brown Leghorn which have been immunized by S. mutan. Agar gel precipitation test was done to detect IgY anti S. <em>mutans </em>in serum and egg. Egg which Countain IgY anti S. <em>mutans </em>was collected. IgY anti S. <em>mutans</em> extracted from egg yolk by mean s PEG-Amonium sulfat and purified using fast protein liquid chromatography. The purity of Igy anti S<em>. mutans</em> was determined by UV spectropometer. Biological activities of Igy anti S. <em>mutans</em> to inhibit adhession process was learned by anti adhesion test. We use two dose of IgY, which is 100 ug and 500 ug. Igy anti S.  <em>mutans </em>formen in serum  five weeks after the first immunization while it formed in egg nine weeks after the first immunization. Igy anti S. <em>mutanss </em>still present in serum andegg until twelve weeks from the first immunization. Igy anti S. <em>mutanss  </em>could decrease the amount of bacteria which attach the epithelial cell surface. The amount of sticky bacteria on epithelial cell (without IgY) are 40 cell bacteria/epithelial cell. After blocked by IgY anti S. <em>mutanss  </em>the amount of bacteria turn into 30 cell bacteria/epithelial cell (for dose of 100 ug IgY) and 28 cell bacteria/epitheelial cell (for dose of 500 ug IgY). This research concluded that hens were capable producing IgY anti S. <em>mutanss </em>in egg yolk and it can be used to solve dental caries problem which caused by S. <em>mutanss.</em><em></em></p&gt;}, number={3}, journal={Jurnal Ilmu Pertanian Indonesia}, author={PoetriOkti Nadia and SoejoedonoRetno D}, year={1}, month={1}, pages={6-10} }