Kidney Bean Yoghurt is Effective to Improve Immune System and Sleep Quality Among Elderly in Yogyakarta
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Issue
Vol. 14 No. 3 (2019)
Accepted
26 November 2019
Published
26 November 2019
Keywords:
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elderly, kidney bean, lymphocyte, sleep quality, yoghurt
Abstract
This study aimed to assess the effect of kidney bean yoghurt on the immune system and sleep quality in healthy elderly subjects in Yogyakarta. The study included 17 healthy elderly aged 60-81 years. The study design was a quasi-experimental, before and after design conducted at the Abiyoso Institutional Care for elderly in Yogyakarta from April to May 2018. The subjects were given 200 ml kidney bean yoghurt everyday for 14 days. The immune system status was measured by lymphocyte count and the sleep quality was measured by the PSQI with higher scores in dicating worse sleep quality. Paired t-test was used for data analysis. Lymphocyte count after intervention (28.89±7.09) was higher than before intervention (25.96±7.41), and it was statistically significant (p=0.006). The sleep quality index after the intervention (4.88±1.83) was lower than before intervention (8.06±3.09) and the difference was statistically significant (p=0.001). This intervention study indicates that kidney bean yoghurt significantly improves both immune systems and sleeps quality among our elderly subjects.
References
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Improvement of nutritional status and incidence of infection in hospitalized, enterally fed elderly by feeding of fermented milk containing probiotic Lactobacillus johnsonii La1 (NCC533). Br J Nutr 98(5):969–977. https://doi.org/10.1017/S0007114507764723.
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Maryam RS, Ekasari MF, Rosidawati, Jubaedi A, Batubara I. 2008. Mengenal Usia Lanjut dan Perawatannya. Jakarta: Salemba Medika.
Mocchegiani E, Giacconi R, Cipriano C, Malavolta M. 2009. NK and NKT cells in aging and longevity: Role of zinc and metallothioneins. J Clin Immunol 29(4):416–425.
Mora JR, Iwata M, Von Andrian UH. 2008. Vitamin effects on the immune system: Vitamins A and D take centre stage. Nat Rev Immuno 8(9):685–698.
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Nugroho W. 2008. Keperawatan Gerontik dan Geriatrik Edisi 3. Jakarta: EGC.
Putriningtyas ND dan Wahyuningsih S. 2017. Potensi yogurt kacang merah (Phaseolus vulgaris L) ditinjau dari sifat organoleptik, kandungan protein, lemak dan flavonoid. Jurnal Gizi Indonesia 6(1):37–43.
Ravagglia G, Forti P, Maioli F, Bastagli L, Facchini A, Mariani E, Savarino L, Sassi S, Cucinotta D, Lenaz G. 2000. Effect of micronutrient status on natural killer cell immune function in healthy free living subjects aged ≥90y. Am J Clin Nutr 71(2):590–598.
Roccichelli JT, Sanford JT, Vanewaa E. 2010. Managing sleep disorders in the elderly. Nurse Pract 35(5):30–37.
Sari YR, Juffrie M, Pramantara IDP. 2009. Pemberian seuplemen seng sulfat dan pengaruhnya terhadap kadar seng serum dan jumlah CD4+ pada wanita usia lanjut sehat. JGKI 5(3):101–107.
Smyth C. 2007. The pittburgh sleep quality index (PSQI). Tersedia pada: https://consultgeri.org/try-this/general-assessment/issue-6.1.pdf. [Accessed 10th November 2019].
Wahyuningsih R, Darmono SS, Margawati A. 2014. Pengaruh pemberian probiotik Lactobacillus helveticus Rosell-52 dan Lactobacillus rhamnosus Rosell-11 terhadap kadar limfosit lanjut usia. Jurnal Gizi Indonesia 3(1):13–19.
[WHO] World Health Organization. 2018. Elderly population “Trends in proportion of older persons (60+). South-East Asia. World Health Organization. http://www.searo.who.int/entity/health_situation_trends/data/chi/elderly-population/en/ [Accessed 10th November 2019].
Widiyaningsih EN. 2011. Peran probiotik untuk kesehatan. Jurnal Kesehatan 4(1):14–20.
Yamamura S, Morishima H, Kumano-go T, Suganuma N, Matsumoto H, Adachi H, Sigedo Y, Mikami A, Kai T, Masuyama A, et al. 2009. The effect of Lactobacillus helveticus fermented milk on sleep and health perception in elderly subject. Eur J Clin Nutr 63(1):100–103.
Bengtson VL, Gans D, Putney NM, Silverstein M. 2009. Handbook of Theories of Aging 2nd Edition. New York: Springer Publishing Company, LLC.
Candore G, Balistreri CR, Colonna- Romano G, Grimaldi MP, Lio D, Listi F, Scola L, Vasto S, Caruso C. 2008. Immunosenescence and anti-immunosenescence therapies: The case of probiotics. Rejuvenation Research. 11(2):425–432. https://doi.org/10.1089/rej.2008.0662.
Carole A. 2008. Evaluating sleep quality in older adults: the Pittsburgh sleep quality index can be used to detect sleep disturbances or deficits. Am J Nurs 108(5):42–50. doi: 10.1097/01.NAJ.0000317300.33599.63
Cherasse Y, Saito H, Nagata N, Aritake K, Lazarus M, Urade Y. 2015. Zinc-containing yeast extract promotes nonrapid eye movement sleep in mice. Mol Nutr Food Res 59(10):2087–2093. https://doi.org/10.1002/mnfr.201500082.
Cherasse Y, Urade Y. 2017. Dietary zinc acts as a sleep modulator. Int. J. Mol. Sci. 18(11):2334–2346. https://doi.org/10.3390 /ijms18112334.
Cooke JR, Ancoli- Israel S. 2011. Normal and abnormal sleep in the elderly. Handb Clin Neurol 98:653–665.
Darmojo RB. 2009. Teori Penuaan. Dalam: Martono HH, Pranarka K. Buku Ajar Boedhi Darmojo Geriatri: (Ilmu KesehatanUsia Lanjut) 4th . Jakarta: FKUI.
[Dinkes] Dinas Kesehatan DI Yogyakarta. 2013. Profil Kesehatan Kota Yogyakarta Tahun 2013. Yogyakarta: Dinkes DIY. [Accessed on 10th May 2018].
Dunhoff C. 1998. Sleep may have negative impact on immune system. UPMC News Bureau. Available at: http://www.upmc.com.media/newsreleases/1998/pages/sleep-may-have-negative-impact-on-immune-system.aspx.
Fatmah. 2006. Respons imunitas yang rendah pada tubuh manusia usia lanjut. Makara, Kesehatan 10(1):47–53. https://doi/org/10.7454/msk.v10i1.169
Fatmah. 2010. Nutrition for Eldery. Jakarta: Erlangga.
Forssten SD, Salazar N, Lopez P, Nikkilä J, Ouwehand AC, Patterson A, Ruas- Madiedo P, Suarez A, Gonzalez S, Gueimonde M. 2011. Influence of a probiotik milk drink, containing Lactobacillus paracasei Lpc-37, on Immune function and gut microbiota in elderly subjects. European J Nutr Food Saf 1(3):159–172.
Fukushima Y, Miyaguchi S, Yamano T, Kaburagi T, Iino H, Ushida K, Sato K. 2007.
Improvement of nutritional status and incidence of infection in hospitalized, enterally fed elderly by feeding of fermented milk containing probiotic Lactobacillus johnsonii La1 (NCC533). Br J Nutr 98(5):969–977. https://doi.org/10.1017/S0007114507764723.
Gill HS, Rutherfurd KJ, Cross ML, Gopal PK. 2001. Enhancement of immunity in the elderly by dietary supplementation with the probiotic Bifidobacterium lactis HN019. Am J Clin Nutr 74(6):833–839. https://doi.org/10.1093/ajcn/74.6.833.
Guillemard E, Tondu F, Lacoin F, Schrezenmeir J. 2010. Consumption of a fermented dairy product containing the probiotic Lactobacillus casei DN-114001 reduces the duration of respiratory infections in the elderly in a randomized controlled trial. Br J Nutr 103(1):58–68. https://doi.org/10.1017/S0007114509991395.
Hadisaputro S, Wibisono BH. 2009. Infeksi Pada Lansia. Dalam: Martono HH, Pranarka K. Buku Ajar Boedhi Darmojo: Geriatri (Ilmu Kesehatan Usia Lanjut) Edisi Ke-4. Jakarta: FKUI.
Herich R, Levkut M. 2002. Lactic acid bacteria, probiotics and immune system. Vet Med 47(6):169–180.
Liu YJ, Zhan J, Liu XL, Wang Y, Jia J, He QQ 2014. Dietary flavonoids intake and risk of type 2 diabetes: A meta-analysis of prospective cohort studies. Clin Nutr 33(1):59–63.
Kazue I, Matsuyama S, Miyake S, Suga K, Nakachi K. 2000. Natural cytotoxic activity of peripheral-blood lymphocytesand cancer incidence: an 11-year follow up study of ageneral population. The Lancet 356(9244):1795–1799. https://doi.org/10.1016/S0140-6736(00)03231-1.
Kwon DY, Hong SM, Ahn IS, Kim YS, Shin DW, Park S. 2009. Kochujang, a Korean fermented red pepper plus soybean paste, improves glucose homeostasis in 90% pancreatectomized diabetic rats. Nutrition 25(7):790–799.
Lauderdale DS, Chen JH, Kurina LM, Waite LJ, Thisted RA. 2016. Sleep duration and health among older adults: Associations vary by how sleep is measured. J Epidemiol Community Health. 70(4): 361–366.
Makino S, Ikegami S, Kume A, Horiuchi H, Sasaki H, Orii N. 2010. Reducing the risk of infection in the elderly by dietary intake of yoghurt fermented with Lactobacillus delbrueckii ssp. Blgaricus OLL1073R-1. Br J Nutr 104(7):998–1006. doi:10.1017/S000711451000173X.
Maryam RS, Ekasari MF, Rosidawati, Jubaedi A, Batubara I. 2008. Mengenal Usia Lanjut dan Perawatannya. Jakarta: Salemba Medika.
Mocchegiani E, Giacconi R, Cipriano C, Malavolta M. 2009. NK and NKT cells in aging and longevity: Role of zinc and metallothioneins. J Clin Immunol 29(4):416–425.
Mora JR, Iwata M, Von Andrian UH. 2008. Vitamin effects on the immune system: Vitamins A and D take centre stage. Nat Rev Immuno 8(9):685–698.
National Sleep Foundation. 2003. Sleep in America poll. March 10, 2003. https://www.sleepfoundation.org/sites/default/files/inlinefiles/2003SleepPollExecSumm.pdf. [Accessed 10th November 2019].
Nugroho W. 2008. Keperawatan Gerontik dan Geriatrik Edisi 3. Jakarta: EGC.
Putriningtyas ND dan Wahyuningsih S. 2017. Potensi yogurt kacang merah (Phaseolus vulgaris L) ditinjau dari sifat organoleptik, kandungan protein, lemak dan flavonoid. Jurnal Gizi Indonesia 6(1):37–43.
Ravagglia G, Forti P, Maioli F, Bastagli L, Facchini A, Mariani E, Savarino L, Sassi S, Cucinotta D, Lenaz G. 2000. Effect of micronutrient status on natural killer cell immune function in healthy free living subjects aged ≥90y. Am J Clin Nutr 71(2):590–598.
Roccichelli JT, Sanford JT, Vanewaa E. 2010. Managing sleep disorders in the elderly. Nurse Pract 35(5):30–37.
Sari YR, Juffrie M, Pramantara IDP. 2009. Pemberian seuplemen seng sulfat dan pengaruhnya terhadap kadar seng serum dan jumlah CD4+ pada wanita usia lanjut sehat. JGKI 5(3):101–107.
Smyth C. 2007. The pittburgh sleep quality index (PSQI). Tersedia pada: https://consultgeri.org/try-this/general-assessment/issue-6.1.pdf. [Accessed 10th November 2019].
Wahyuningsih R, Darmono SS, Margawati A. 2014. Pengaruh pemberian probiotik Lactobacillus helveticus Rosell-52 dan Lactobacillus rhamnosus Rosell-11 terhadap kadar limfosit lanjut usia. Jurnal Gizi Indonesia 3(1):13–19.
[WHO] World Health Organization. 2018. Elderly population “Trends in proportion of older persons (60+). South-East Asia. World Health Organization. http://www.searo.who.int/entity/health_situation_trends/data/chi/elderly-population/en/ [Accessed 10th November 2019].
Widiyaningsih EN. 2011. Peran probiotik untuk kesehatan. Jurnal Kesehatan 4(1):14–20.
Yamamura S, Morishima H, Kumano-go T, Suganuma N, Matsumoto H, Adachi H, Sigedo Y, Mikami A, Kai T, Masuyama A, et al. 2009. The effect of Lactobacillus helveticus fermented milk on sleep and health perception in elderly subject. Eur J Clin Nutr 63(1):100–103.
Authors
PutriningtyasN. D., & AstutiA. T. (2019). Kidney Bean Yoghurt is Effective to Improve Immune System and Sleep Quality Among Elderly in Yogyakarta. Jurnal Gizi Dan Pangan, 14(3), 141-148. https://doi.org/10.25182/jgp.2019.14.3.141-148
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