Asosiasi c.248 A>G gen CD1B dengan IgY dan Titer ND pada Ayam Sentul Galur Sensi-1 Agrinak

  • M. F. Al-Habib Departemen Ilmu Produksi dan Teknologi Peternakan, Fakultas Peternakan, Institut Pertanian Bogor
  • S. Murtini Department of Animal Disease and Veterinary Public Health, Faculty Veterinary Medicine, IPB University
  • A. Gunawan Departemen Ilmu Produksi dan Teknologi Peternakan, Fakultas Peternakan, Institut Pertanian Bogor
  • N. Ulupi Departemen Ilmu Produksi dan Teknologi Peternakan, Fakultas Peternakan, Institut Pertanian Bogor
  • C. Sumantri Departemen Ilmu Produksi dan Teknologi Peternakan, Fakultas Peternakan, Institut Pertanian Bogor

Abstract

The aim of this study was to identify the polymorphism of the CD1B gene in c.248 in exon 3 and its association with IgY and ND titers in sentul chicken Sensi-1 Agrinak line. IgY is the main antibody of chickens while the ND titer is an ND specific antibody, both of which have an important role in the response of disease resistance. The Cluster of differentiation 1B (CD1B) gene is one of the major genes of disease resistance that functions in representing antigens through specific immune responses. This study used 17 sensi-1 chicken lines. The study was conducted by PCR sequencing method, ELISA test, and HI test. The result showed mutation on c248 A>G in exon 3. The SNP were polymorphic and Hardy Weinberg equilibrium. Thre were two A and G alleles and 3 genotypes namely AG, GG, and AA. The frequency of the GG genotype was higher (0.41) compared to other genotypes. The AG genotype were associated with IgY production and were not associated with ND titers.

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Published
2020-01-31
How to Cite
M. F. Al-Habib, S. Murtini, A. Gunawan, N. Ulupi, & C. Sumantri. (2020). Asosiasi c.248 A>G gen CD1B dengan IgY dan Titer ND pada Ayam Sentul Galur Sensi-1 Agrinak. Jurnal Ilmu Produksi Dan Teknologi Hasil Peternakan, 8(1), 30-35. https://doi.org/10.29244/jipthp.8.1.30-35