JIPI
Skip to main content Skip to main navigation menu Skip to site footer

Pengetahuan Tentang Manfaat Kesehatan Temulawak (Curcuma xanthorrhiza.) Serta Uji Klinis Pengaruhnya pada Sistem Imun Humoral pada Dewasa Obes

  • Mira Dewi
  • Muhammad Aries
  • . Hardinsyah
  • Cesilia Meti Dwiriani
  • Nunuk Januwati
Keywords: health benefits, humoral immune system, knowledge, temulawakc

Abstract

Sufficient knowledge of the community regarding benefits of temulawak for health and scientific evidence of its influence on the immune system is crucial for rationalizing the utilization of these plants for health purposes. This study aimed to analyze the public's knowledge about health benefits of temulawak drinks, as well as analyzing the effect of temulawak extract drink consumption on humoral immune system function as assessed by population of B lymphocytes in obese adults. The study consisted of a survey of knowledge about the health benefits of temulawak involving 80 subjects and a clinical trial of the effect of extract temulawak drink consumption given for 2 weeks in 21 obese subjects. Populationof total lymphocytes and B lymphocytes were analyzed before and after intervention. This study showed that the health benefits of temulawak most widely known by subjects were to increase appetite and to maintain stamina. From the clinical trial it was shown that the extract significantly reduce the population of B lymphocytes, indicating a decrease in humoral immune function.

Downloads

Download data is not yet available.

Author Biographies

Mira Dewi
Departemen Gizi Masyarakat, Fakultas Ekologi Manusia, Institut Pertanian Bogor, Kampus IPB Dramaga, Bogor 16680
Muhammad Aries
Departemen Gizi Masyarakat, Fakultas Ekologi Manusia, Institut Pertanian Bogor, Kampus IPB Dramaga, Bogor 16680
. Hardinsyah
Departemen Gizi Masyarakat, Fakultas Ekologi Manusia, Institut Pertanian Bogor, Kampus IPB Dramaga, Bogor 16680
Cesilia Meti Dwiriani
Departemen Gizi Masyarakat, Fakultas Ekologi Manusia, Institut Pertanian Bogor, Kampus IPB Dramaga, Bogor 16680
Nunuk Januwati
Balai Penelitian Tanaman Obat dan Aromatika, Deptan RI, Jl. Tentara Pelajar No. 3, Kampus Penelitian Pertanian Cimanggu, Bogor 16111

References

Abbas AK, Lichtman AH. 2004. Basic Immunology: Functions and dissorders of the immune system. Ed. Ke-2. Philadelphia (US): Saunders.

Baratawidjaja KG, Rengganis I. 2009. Imunologi Dasar. Ed. ke-8. Jakarta (ID): Balai Penerbit Fakultas Kedokteran Universitas Indonesia.

Dwiriani CM, Dewi M, Januwati NM, Sulaeman A. 2010. Efikasi Ekstrak Temulawak (Curcuma xanthorrhiza Roxb.) Berbahan Aktif Xanthorrhizol (0,05%) untuk Meningkatkan Populasi Limfosit T (>10%) pada Dewasa Obes. [laporan penelitian]. Bogor (ID): Departemen Pertanian RI.

Dhaliwal JS, Balasubramaniam T, Quek CK, Gill HK, Nasuruddin BA. 1995. Reference range for lymphocyte subsets in a defined Malaysian population. Singapore Med J. 36: 288-291.

Hendarini AT. 2011. Persepsi masyarakat terhadap manfaat kesehatan dan pengembangan produk minuman fungsional dari ekstrak daun hantap (Sterculia oblongata R.Brown). [Tesis]. Bogor (ID): Institut Pertanian Bogor.

Huang MT, Lysz T, Ferraro T, Abidi TF, Laskin JD, Conney AH. 1991. Inhibitory effects of curcumin on in vitro lipoxygenase and cyclooxygenase activities in mouse epidermis. Cancer Res. 51(3): 813-819.

Damayanti R. 2008. Uji efek sediaan serbuk instan rimpang temulawak (Curcuma xanthorrhiza) sebagai tonikum terhadap mencit jantan. [Skripsi]. Surakarta (ID): Universitas Muhammadiyah Surakarta.

Smith AG, Sheridan PA, Harp JB, Beck MA. 2007. Diet-induced obese mice have increased mortality and altered immune responses when infected with influenza virus. J Nutr. 137: 1236-1243.

Khomsan A. 2000. Teknik Pengukuran Pengetahuan Gizi. Bogor (ID): Institut Pertanian Bogor.

Kim AJ, Kim YO, Shim JS, Hwang JK. 2007. Immunostimulating activity of crude polysaccharide extract isolated from Curcuma xanthorrhixa Roxb. Biosci Biotechnol Biochem. 71(6): 1428-1438.

Kosim L, Priosoeryanto BP, Purwakusumah ED. 2007. Potensi Temulawak Testandar Untuk Menanggulangi Flu Burung. [Laporan penelitian]. Bogor (ID): Pusat Studi Biofarmaka, Institut Pertanian Bogor.

Kuntorini EM. 2005. Botani ekonomi suku Zingiberaceae sebagai obat tradisional oleh masyarakat di Kotamadya Banjarbaru. Bioscientiae. 2(1) [diunduh 2011 Apr 27] tersedia pada http://bioscientiae. tripod.com.

Septina T, Purba M, Hartriyanti Y. 2010. Studi validasi indeks massa tubuh dan rasio lingkar pinggang panggul terhadap profil lipid pada pasien rawat jalan di Poli Jantung RSUP Dr. Sardjito Yogyakarta. J Gizi Klin Indones. 7(1): 34-40.

Uppal SS, Verma S, Dhot PS. 2003. Normal values of CD4 and CD8 lymphocyte subsets in healthy indian adults and the effects of sex, age, ethnicity, and smoking. Cytometry B Clin Cytom. 52(1): 32-36.

Published
2014-08-23
How to Cite
Dewi, M., Aries, M., Hardinsyah, ., Dwiriani, C. M., & Januwati, N. (2014). Pengetahuan Tentang Manfaat Kesehatan Temulawak (Curcuma xanthorrhiza.) Serta Uji Klinis Pengaruhnya pada Sistem Imun Humoral pada Dewasa Obes. Jurnal Ilmu Pertanian Indonesia, 17(3), 166-171. Retrieved from http://journal.ipb.ac.id/index.php/JIPI/article/view/8337

Most read articles by the same author(s)

<< < 2 3 4 5 > >>